METHOD AND KIT FOR DETECTING BCR-ABL FUSION GENE MUTATION USING PNA-BASED REAL-TIME PCR CLAMPING
摘要
The present invention relates to a method for selectively detecting only mutation, by using a PNA (peptide nucleic acid) probe that binds specifically to the wild-type codon 315 (T315) of the ABL gene exon 6 in a BCR-ABL fusion gene, such that wild-type amplification is inhibited. The present invention also relates to a kit for use with the method.
申请公布号
WO2012064035(A2)
申请公布日期
2012.05.18
申请号
WO2011KR08056
申请日期
2011.10.27
申请人
PANAGENE INC.;PARK, HEE KYUNG;CHOI, JAE JIN;KIM, HYUN SUN;JANG, MIN JUNG
发明人
PARK, HEE KYUNG;CHOI, JAE JIN;KIM, HYUN SUN;JANG, MIN JUNG