发明名称 |
CIRCUMFERENTIAL AEROSOL DEVICE FOR DELIVERING DRUGS TO OLFACTORY EPITHELIUM AND BRAIN |
摘要 |
Methods of delivering a pharmaceutical compounds directly to the olfactory epithelium of a mammal by providing a pharmaceutical aerosol suspension comprising an aerosol and the pharmaceutical compound; aerosolizing the suspension to generate a stream of droplets, the stream having a rotational component, and, delivering the droplets directly to the olfactory epithelium, wherein at least 15% of the droplets are delivered directly to the olfactory deposition. The pharmaceutical compound may be encapsulated within a liposome nanoparticle. |
申请公布号 |
WO2012024595(A3) |
申请公布日期 |
2012.05.18 |
申请号 |
WO2011US48435 |
申请日期 |
2011.08.19 |
申请人 |
UNIVERSITY OF WASHINGTON;HOEMAN, JOHN D.;HO, RODNEY, J.Y. |
发明人 |
HOEMAN, JOHN D.;HO, RODNEY, J.Y. |
分类号 |
A61M15/08;A61M11/02;A61M19/00 |
主分类号 |
A61M15/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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