发明名称 |
DETERMINING SENSITIVITY OF CELLS TO B-RAF INHIBITOR TREATMENT BY DETECTING KRAS MUTATION AND RTK EXPRESSION LEVELS |
摘要 |
<p>The present invention relates to prognostic methods for identifying tumors that are not susceptible to B-Raf inhibitor treatment by detecting mutations in a K-ras gene or protein or by detecting overexpression of RTKs and/or their ligands. Kits are also disclosed for carrying out the methods.</p> |
申请公布号 |
KR20120050493(A) |
申请公布日期 |
2012.05.18 |
申请号 |
KR20127007529 |
申请日期 |
2010.08.24 |
申请人 |
GENENTECH, INC. |
发明人 |
HATZIVASSILIOU GEORGIA;MALEK SHIVA |
分类号 |
G01N33/574;C12Q1/68 |
主分类号 |
G01N33/574 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|