发明名称 SENSITIZER AND ERYTHROCYTIC DIAGNOSTIC AGENT FOR DIAGNOSING MALIGNANT NEOPLASMS, METHODS FOR PRODUCING SAME
摘要 The invention relates to medicine. The sensitizer for an erythrocytic diagnostic agent for diagnosing the presence of malignant neoplasms comprises a mixture of fractions of low-molecular protein compounds with a molecular mass of 3000-15000 Da, which is extracted from the blood serum of a pregnant mare in the early stage of pregnancy and exhibits a stimulating effect on the proliferation of malignant cells. The method for producing the sensitizer includes obtaining the serum, fractionating same by liquid chromatography and extracting a mixture of fractions of protein compounds with a molecular mass of 3000-15000 Da. The erythrocytic diagnostic agent contains formalized sheep erythrocytes sensitized with the aforementioned sensitizer. The method for producing the diagnostic agent includes sensibilizing a suspension of formalized erythrocytes with the sensitizer. The method for diagnosing the presence of malignant neoplasms is carried out using the aforementioned erythrocytic diagnostic agent.
申请公布号 WO2012030256(A3) 申请公布日期 2012.05.18
申请号 WO2011RU00655 申请日期 2011.08.29
申请人 BALYURA, ALEXANDR VLADIMIROVICH;MOLODYK, ALVINA ALFREDOVNA;SAVLUCHYNSKAYA, LYUDMILA ALEXANDROVNA;TARASOV, SERGEY GENNADEVICH 发明人 BALYURA, ALEXANDR VLADIMIROVICH;MOLODYK, ALVINA ALFREDOVNA;SAVLUCHYNSKAYA, LYUDMILA ALEXANDROVNA;TARASOV, SERGEY GENNADEVICH
分类号 G01N33/574;A61K38/02;C07K1/16;G01N33/556;G01N33/68 主分类号 G01N33/574
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