摘要 |
<P>PROBLEM TO BE SOLVED: To provide inhibitors of protein kinase. <P>SOLUTION: There are provided new compounds useful as inhibitors of protein kinase represented by formula (I) and pharmaceutically acceptable salts thereof, wherein A, R<SP POS="POST">a</SP>, R<SP POS="POST">b</SP>, R<SP POS="POST">c</SP>, R<SP POS="POST">d</SP>, G<SP POS="POST">1</SP>, Y<SP POS="POST">1</SP>and Y<SP POS="POST">2</SP>have meanings described in the scope of claims. The pharmaceutical compositions comprising the compounds and methods of using the compositions in the treatment of various diseases are also provided. The compounds are useful for inhibiting kinase activity in vitro or in vivo, and are especially useful for the treatment of various proliferative diseases. <P>COPYRIGHT: (C)2012,JPO&INPIT |