发明名称 METHODS OF TREATING PATIENTS SUFFERING FROM MOVEMENT DISORDERS
摘要 Methods of treating movement disorders by administering an effective amount of one or more adenosine A2A receptor antagonists to a patient in need thereof and methods of decreasing the adverse effects of L-DOPA in patients receiving L-DOPA therapy in the treatment of Parkinson's disease. Also, methods and compositions for treating Parkinson's disease patients with sub-clinically effective doses of L-DOPA with an effective amount of one or more adenosine A2A receptor antagonists, optionally with a dopamine agonist and/or a COMT inhibitor and/or a MAO inhibitor.
申请公布号 US2012122897(A1) 申请公布日期 2012.05.17
申请号 US201113297341 申请日期 2011.11.16
申请人 KASE HIROSHI;MORI AKIHISA;WAKI YUTAKA;OHSAWA YUTAKA;KARASAWA AKIRA;KUWANA YOSHIHISA;KYOWA HAKKO KIRIN CO., LTD. 发明人 KASE HIROSHI;MORI AKIHISA;WAKI YUTAKA;OHSAWA YUTAKA;KARASAWA AKIRA;KUWANA YOSHIHISA
分类号 A61K31/522;C07D473/06;A61K45/00;A61P25/00;A61P25/14;A61P25/16 主分类号 A61K31/522
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