发明名称 Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors
摘要 The present invention provides a compound of formula I; or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, A1, X, X1, s and n are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides pharmaceutical composition of the compounds of the invention and a combination of pharmacologically active agents and a compound of the invention.
申请公布号 US2012122977(A1) 申请公布日期 2012.05.17
申请号 US201113294262 申请日期 2011.11.11
申请人 COPPOLA GARY MARK;KARKI RAJESHRI GANESH;KAWANAMI TOSHIO;NOVARTIS AG 发明人 COPPOLA GARY MARK;KARKI RAJESHRI GANESH;KAWANAMI TOSHIO
分类号 A61K31/216;A61K31/194;A61P1/00;A61P3/00;A61P3/04;A61P3/10;A61P7/10;A61P9/00;A61P9/04;A61P9/06;A61P9/10;A61P9/12;A61P11/06;A61P13/12;A61P15/00;A61P25/08;A61P25/18;A61P25/24;A61P25/28;A61P27/02;A61P27/06;A61P29/00;A61P35/02;C07C235/78 主分类号 A61K31/216
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