| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a compound which acts as a glucokinase activator, and which is used for a diabetes-related treatment. <P>SOLUTION: This heteroaryl amide derivative is represented by formula (1B) (in formula, R<SP POS="POST">1</SP>is H, methyl, -CF<SB POS="POST">3</SB>, -S(O)<SB POS="POST">2</SB>CH<SB POS="POST">3</SB>and so on; R<SP POS="POST">2</SP>is cyclopentyl or tetrahydropyranyl; and R<SP POS="POST">4</SP>is pyrazolyl, isooxazolyl, pyridinyl, pyrazinyl, pyrimidinyl, quinolinyl and so on). <P>COPYRIGHT: (C)2012,JPO&INPIT |
