发明名称 SUBSTITUTED CARBAMOYLCYCLOALKYL ACETIC ACID DERIVATIVES AS NEP
摘要 The present invention provides a compound of formula I; or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, B, X, m and n are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides pharmaceutical composition of compounds of the invention, and a combination of pharmacologically active agents and a compound of the invention.
申请公布号 US2012122764(A1) 申请公布日期 2012.05.17
申请号 US201113293560 申请日期 2011.11.10
申请人 KARKI RAJESHRI GANESH;KAWANAMI TOSHIO;KSANDER GARY MICHAEL;LIU QIAN;MOGI MUNETO;SCHIERING NIKOLAUS;SUN ROBERT;NOVARTIS AG 发明人 KARKI RAJESHRI GANESH;KAWANAMI TOSHIO;KSANDER GARY MICHAEL;LIU QIAN;MOGI MUNETO;SCHIERING NIKOLAUS;SUN ROBERT
分类号 A61K38/05;A61K31/194;A61K31/216;A61K31/41;A61K31/437;A61K31/4418;A61P1/00;A61P1/16;A61P3/00;A61P3/04;A61P3/10;A61P5/42;A61P9/00;A61P9/04;A61P9/06;A61P9/10;A61P9/12;A61P11/06;A61P13/12;A61P15/00;A61P25/08;A61P25/18;A61P25/24;A61P27/06;A61P29/00;A61P35/02;C07C235/82;C07D207/16;C07D213/56;C07D257/04;C07D295/195;C07D471/04 主分类号 A61K38/05
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