发明名称 Novel Peptidase Substrates
摘要 The present invention relates to the use of a compound of the following formula (I) for detecting a peptidase activity and/or a variation in pH: according to which: Y1 is a peptide, H or an alkyl; W1, W2, W3 and W4 are independently H, Br, Cl, F, I, alkyl, alkoxy, thiomethyl, perfluoroalkyl, nitro, cyano, carboxyl (including the esters or amides thereof) or any combination thereof; n=0, 1 or 2; U and V are N, N+R or CZ4, R being H, alkyl, aralkyl, aryl, alkanoyl or alkylsulfonyl; Z1, Z2, Z3 and Z4 being independently H, Br, Cl, F, I, alkyl, aryl, alkoxy, perfluoroalkyl, nitro, cyano, carboxyl, sulfonyl, including the carboxyl or sulfonyl esters or amides, and salts thereof.
申请公布号 US2012122134(A1) 申请公布日期 2012.05.17
申请号 US201013386578 申请日期 2010.07.28
申请人 JAMES ARTHUR;ORENGA SYLVAIN;PERRY JOHN;SALWATURA VINDHYA;STANFORTH STEPHEN;BIOMERIEUX SA 发明人 JAMES ARTHUR;ORENGA SYLVAIN;PERRY JOHN;SALWATURA VINDHYA;STANFORTH STEPHEN
分类号 C12Q1/37;C07D221/00;C07K17/02 主分类号 C12Q1/37
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