发明名称 |
DRUG-LOADED POLYSACCHARIDE-COATED GOLDMAG PARTICLES (DPGPs) AND ITS SYNTHESIS METHOD |
摘要 |
The invention relates to Polysaccharide-coated GoldMag particles (DPGPs) and the method of its synthesis, which characterized GoldMag particles as a core and natural or synthetic biodegradable polysaccharide such as dextran, cyclodextrin and derivatives as shell. DPGPs are synthesized by mixing Polysaccharide-coated GoldMag particles (DPGPs) with drug through physical bond. The preparation of the drug-loaded composite particles include: preparing the polysaccharide-coated GoldMag particles and then loading the drug on the polysaccharide-coated GoldMag particles. The drug-loading process is carried out through directly mixing the polysaccharide-coated GoldMag particles with the drug solution by the shaker. That means the polysaccharide-coated GoldMag particles load the drug through affinity adsorption. |
申请公布号 |
US2012121717(A1) |
申请公布日期 |
2012.05.17 |
申请号 |
US200813142820 |
申请日期 |
2008.12.30 |
申请人 |
CHAO XU;CUI YALI;PENG MINGLI;CHEN CHAO;XIN XIAOFANG;LI KE;HUI WENLI;XI'AN GOLDMAG NANOBIOTECH CO. LTD |
发明人 |
CHAO XU;CUI YALI;PENG MINGLI;CHEN CHAO;XIN XIAOFANG;LI KE;HUI WENLI |
分类号 |
A61K9/14;A61K31/704;A61P31/00;A61P35/00;B05D3/00 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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