| 发明名称 |
METHOD FOR TREATING CANCER BY INCREASING AMP-ACTIVATED KINASE ACTIVITY |
| 摘要 |
The invention relates to modulation of LKB1 or AMP kinase protein activity for treating disorders including diabetes and cancer. The invention also relates to screening for agents that modulate the activity of LKB1 or AMP kinase protein, which are useful in the treatment of diabetes and cancer, as well as preparing compounds for treatment of diabetes and cancer.
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| 申请公布号 |
US2012122991(A1) |
申请公布日期 |
2012.05.17 |
| 申请号 |
US201213354953 |
申请日期 |
2012.01.20 |
| 申请人 |
CANTLEY LEWIS C.;SHAW REUBEN J.;BARDEESY NABEEL;DEPINHO RONALD A.;DANA-FARBER CANCER INSTITUTE, INC.;BETH ISRAEL DEACONESS MEDICAL CENTER, INC. |
发明人 |
CANTLEY LEWIS C.;SHAW REUBEN J.;BARDEESY NABEEL;DEPINHO RONALD A. |
| 分类号 |
A61K31/155;A61K;A61P35/00;C12Q1/48;G01N33/573;G01N33/574 |
主分类号 |
A61K31/155 |
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