发明名称 |
METHOD FOR MODIFICATION OF NUCLEOTIDES IN NUCLEIC ACID, AND NUCLEIC ACID HAVING MODIFIED NUCLEOTIDE THEREIN |
摘要 |
A method for modifying nucleic acid bases by a chemical means, which enables the discrimination of every base species in plural species of bases in a nucleic acid comprising plural nucleotide units, while retaining the base sequence information of the nucleic acid. A nucleic acid base-modified product provided by the method. The nucleic acid base-modified product is essentially a single strand. In accordance with the invention, a novel means for sequencing a nucleic acid by a microscopic means is provided. |
申请公布号 |
EP2189468(A4) |
申请公布日期 |
2012.05.16 |
申请号 |
EP20080826911 |
申请日期 |
2008.08.08 |
申请人 |
INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION NATIONAL INSTITUTES OF NATURAL SCIENCES;NAGAYAMA IP HOLDINGS, LLC |
发明人 |
KATAOKA, MASANORI;NAGAYAMA, KUNIAKI |
分类号 |
C07H21/00;C07F9/6561;C12Q1/68;G01N33/58 |
主分类号 |
C07H21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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