发明名称 |
NEUTRALISIERUNG MONOKLONALER ANTIKÖRPER GEGEN MIT SCHWEREM AKUTEM RESPIRATIONSSYNDROM ASSOZIIERTEM CORONAVIRUS |
摘要 |
<p>The present invention provides an isolated antibody capable of binding to the receptor- binding domain of the spike protein of the severe acute respiratory syndrome-associated coronavirus (SARS-CoV) so as to competitively inhibit the binding of the SARS-CoV to host cells. These mAbs or substances can be used: 1) as passive-immunizing agents for prevention of SARS-CoV infection; 2) as biological reagents for diagnosis of SARS-CoV infection; 3) as immunotherapeutics for early treatment of SARS-CoV infection; and 4) as probes for studying the immunogenicity, antigenicity, structure, and function of the SARS- CoV S protein.</p> |
申请公布号 |
AT556717(T) |
申请公布日期 |
2012.05.15 |
申请号 |
AT20100151641T |
申请日期 |
2006.02.08 |
申请人 |
THE NEW YORK BLOOD CENTER, INC. |
发明人 |
JIANG, SHIBO;HE, YUXIAN |
分类号 |
A61K39/00;A61K39/215;C07K16/10 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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