发明名称 C-MET ANTIBODY COMBINATIONS
摘要 The invention provides a product combination or composition, and also multispecific antibodies comprising two or more antigen-binding sites (as antibodies or antigen binding fragments thereof), wherein two the antigen-binding bind to distinct non-overlapping epitopes of the human c-Met protein. The product combination or composition or multispecific antibody inhibits HGF-independent activation of the human c-Met receptor protein.
申请公布号 WO2012059562(A1) 申请公布日期 2012.05.10
申请号 WO2011EP69372 申请日期 2011.11.03
申请人 ARGEN-X-BV;HULTBERG, ANNA;SAUNDERS, MICHAEL;DE HAARD, JOHANNES;FESTJENS, ELS;DE JONGE, NATALIE;MICHIELI, PAULO;BASILICO, CRISTINA;DREIER, TORSTEN 发明人 HULTBERG, ANNA;SAUNDERS, MICHAEL;DE HAARD, JOHANNES;FESTJENS, ELS;DE JONGE, NATALIE;MICHIELI, PAULO;BASILICO, CRISTINA;DREIER, TORSTEN
分类号 C07K16/28;A61K39/395;A61P35/00;C07K16/46 主分类号 C07K16/28
代理机构 代理人
主权项
地址