STABILIZED STEP FUNCTION OPSIN PROTEINS AND METHODS OF USING THE SAME
摘要
Provided herein are compositions comprising non-human animals comprising neurons expressing stabilized step function opsin proteins on neural plasma membranes and methods of using the same to selectively depolarize neurons residing in microcircuits of the pre-frontal cortex to affect one or more social behaviors, communications, and/or conditioned behaviors in the non-human animal.
申请公布号
WO2012061744(A2)
申请公布日期
2012.05.10
申请号
WO2011US59390
申请日期
2011.11.04
申请人
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;DEISSEROTH, KARL;YIZHAR, OFER;FENNO, LIEF