发明名称 VACCINE IMMUNOTHERAPY FOR IMMUNE SUPPRESSED PATIENT
摘要 <P>PROBLEM TO BE SOLVED: To provide a consistent and effective method for immunizing a cancer patient. <P>SOLUTION: A method for overcoming mild to moderate immune suppression includes the steps of inducing production of naive T-cells and restoring T-cell immunity. A method of vaccine immunotherapy includes the steps of inducing production of naive T-cells and exposing the naive T-cells to endogenous or exogenous antigens at an appropriate site. Additionally, a method for unblocking immunization at a regional lymph node includes steps of promoting differentiation and maturation of immature dendritic cells at a regional lymph node and allowing presentation of processed peptides by resulting mature dendritic cells, thus, for example, exposing tumor peptides to T-cells to gain immunization of the T-cells. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012087150(A) 申请公布日期 2012.05.10
申请号 JP20120020558 申请日期 2012.02.02
申请人 IRX THERAPEUTICS INC 发明人 HADDEN JOHN W
分类号 A61K39/00;A61K45/00;A61K31/192;A61K31/365;A61K31/405;A61K31/415;A61K31/664;A61K38/00;A61K38/19;A61K39/39;A61P31/00;A61P31/04;A61P35/00;C12N15/19;C12P21/08 主分类号 A61K39/00
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