发明名称 |
MMP8 INACTIVATING ANTIGEN BINDING PROTEINS |
摘要 |
The present disclosure relates to MMP8 inactivating antigen binding proteins, preferably antigen binding proteins comprising an amino acid sequence that comprises (4) framework regions and (3) complementary determining regions; it relates further to the use of such antigen binding proteins to treat inflammation, such as but not limited to systemic inflammatory response syndrome, sepsis, LPS induced inflammation, renal ischemia/reperfusion injury, ventilation induced lung injury, periodontal inflammation, rheumatoid arthritis, multiple sclerosis, ankylosing spondylitis, lyme arthritis and osteoarthritis. |
申请公布号 |
WO2012059513(A1) |
申请公布日期 |
2012.05.10 |
申请号 |
WO2011EP69238 |
申请日期 |
2011.11.02 |
申请人 |
VIB VZW;UNIVERSITEIT GENT;LIBERT, CLAUDE;DEJONCKHEERE, ELINE;VANDENBROUCKE, ROOSMARIJN |
发明人 |
LIBERT, CLAUDE;DEJONCKHEERE, ELINE;VANDENBROUCKE, ROOSMARIJN |
分类号 |
C07K16/40;A61K39/395;A61P37/00 |
主分类号 |
C07K16/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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