A method of searching for potentially unknown metabolites of pharmaceutical compounds is disclosed. The accurate mass of a pharmaceutical compound will generally be known and can be rendered in the form of an integer nominal mass or mass to charge ratio component and a decimal mass or mass to charge ratio component. Possible metabolites are searched for on the basis of having a decimal mass or mass to charge ratio component which is substantially very similar to the decimal mass or mass to charge ratio of the parent pharmaceutical compound.
申请公布号
US2012112055(A1)
申请公布日期
2012.05.10
申请号
US201113253312
申请日期
2011.10.05
申请人
CASTRO-PEREZ JOSE M.;MILLAR ALAN;PLUMB ROBERT S.;MICROMASS UK LIMITED