| 发明名称 |
CUSTOM-MADE MEGANUCLEASE AND USE THEREOF |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide rare-cutting endonucleases, also called custom-made meganucleases, which recognize and cleave a specific nucleotide sequence. <P>SOLUTION: There are provided: meganuclease variants derived from an initial meganuclease presenting a recognition and cleavage site different from the site of the initial one; polynucleotide encoding the meganuclease variants; recombinant vector cell, animal or plant comprising the polynucleotide sequences; and uses thereof for in vivo or in vitro genetic engineering and genomic engineering. <P>COPYRIGHT: (C)2012,JPO&INPIT |
| 申请公布号 |
JP2012085640(A) |
申请公布日期 |
2012.05.10 |
| 申请号 |
JP20110242304 |
申请日期 |
2011.11.04 |
| 申请人 |
CELLECTIS |
发明人 |
ARNOULD SYLVAIN;BRUNEAU SYLVIA;CABANIOLS JEAN-PIERRE;CHAMES PATRICK;CHOULIKA ANDRE;DUCHATEAU PHILIPPE;EPINAT JEAN-CHARLES;GOUBLE AGNES;LACROIX EMMANUEL;PAQUES FREDERIC;PEREZ-MICHAUT CHRISTOPHE;SMITH JULIANNE;SOURDIVE DAVID |
| 分类号 |
C12N15/09;A01H5/00;A01K67/027;A61K31/7088;A61K38/00;A61K38/46;A61K48/00;A61P31/00;A61P31/12;A61P43/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/16;C12N9/22;C12N15/55;C12N15/85;C12N15/90 |
主分类号 |
C12N15/09 |
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