发明名称 |
OPTICALLY-CONTROLLED CNS DYSFUNCTION |
摘要 |
Provided herein are animals expressing light-responsive opsin proteins in the basal lateral amygdala of the brain and methods for producing the same wherein illumination of the light-responsive opsin proteins causes anxiety in the animal. Also provided herein are methods for alleviating and inducing anxiety in an animal as well as methods for screening for a compound that alleviates anxiety in an animal. |
申请公布号 |
CA2816968(A1) |
申请公布日期 |
2012.05.10 |
申请号 |
CA20112816968 |
申请日期 |
2011.11.04 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNOR UNIVERSITY |
发明人 |
TYE, KAY;FENNO, LIEF;DEISSEROTH, KARL |
分类号 |
C12N15/85;A01K67/027;A61B5/16;A61K38/17;A61P25/22;C07K14/705;C12M1/42;C12N5/10;C12Q1/00 |
主分类号 |
C12N15/85 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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