发明名称 |
COMPOUNDS MODULATORS OF VEGF ACTIVITY AND USES THEREOF |
摘要 |
Compounds of general formula (1): X1Y1X2Y2X3Y3X4Y4Y5X5X6Y6X7Y7X8X9X10 wherein X1-X10 are any natural or unnatural amino acids and Y1 is Gln; Y2 is Met or Leu; Y3 is He; Y4 is Pro or Ser; Y5 is His or Gly; Y6 is Gln or Pro; Y7 is He or Tyr or their homolog or ortolog are described; these compounds are able to bind to the VEGF receptors and to modulate the angiogenesis mediated by the VEG. |
申请公布号 |
US2012114565(A1) |
申请公布日期 |
2012.05.10 |
申请号 |
US201013386506 |
申请日期 |
2010.07.23 |
申请人 |
D'ANDREA LUCA DOMENICO;PEDONE CARLO;TURCO MARIA CATERINA;ADVANCED ACCELERATOR APPLICATIONS S.A. |
发明人 |
D'ANDREA LUCA DOMENICO;PEDONE CARLO;TURCO MARIA CATERINA |
分类号 |
A61K49/14;A61K38/08;A61K49/00;A61P9/00;A61P35/00;C07K7/06;C07K7/08 |
主分类号 |
A61K49/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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