发明名称 |
TRANS-2-DECENOIC ACID DERIVATIVE AND MEDICAMENT CONTAINING SAME |
摘要 |
The purpose of the present invention is to provide a novel trans-2-decenoic acid derivative and a pharmaceutically acceptable salt thereof, and a medicament containing the compound described above as an active component and having a neurotrophic factor-like effect and a side effect reducing effect due to administration of anti-cancer agent which are highly safe. A trans-2-decenoic acid derivative or the pharmaceutically acceptable salt thereof, which is a compound of the present invention, is specifically represented by general formula (1) (where Y represents -O-, -NR-, or -S-, R represents a hydrogen atom, an alkyl group, a dialkylamino group, or the like, and W represents a substituent such as a dialkylaminoalkyl group), and is extremely highly useful as a preventive or therapeutic agent for dementia, Alzheimer's disease, Parkinson's disease, depression and the like, a therapeutic or repairing agent for spinal cord injury, or a medicament such as an agent for reducing the side effect due to administration of anti-cancer agent. |
申请公布号 |
WO2012060396(A1) |
申请公布日期 |
2012.05.10 |
申请号 |
WO2011JP75228 |
申请日期 |
2011.11.01 |
申请人 |
NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE;NIPPON ZOKI PHARMACEUTICAL CO., LTD.;IINUMA, MUNEKAZU;FURUKAWA, SHOEI;NAIKI, MITSURU;MATSUMOTO, TOMONORI;SUGIMOTO, HACHIRO |
发明人 |
IINUMA, MUNEKAZU;FURUKAWA, SHOEI;NAIKI, MITSURU;MATSUMOTO, TOMONORI;SUGIMOTO, HACHIRO |
分类号 |
C07C219/20;A61K31/16;A61K31/165;A61K31/231;A61K31/255;A61K31/40;A61P25/00;A61P25/02;A61P25/14;A61P25/16;A61P25/22;A61P25/24;A61P25/28;A61P43/00;C07C217/08;C07C233/09;C07C233/38;C07C327/30 |
主分类号 |
C07C219/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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