发明名称 |
A buprenorphine transdermal patch for use in the treatment of pain for a dosing interval of at least 7 days |
摘要 |
A sustained release formulation of buprenorphine is new. The composition comprises a transdermal delivery device which provides a first order release of buprenorphine over a 3-day dosing interval so that a maximum plasma concentration of 20 10 1052 pg/ml is obtained. the device then provides zero order kinetics over at least 2 more days. |
申请公布号 |
EP2305194(B1) |
申请公布日期 |
2012.05.09 |
申请号 |
EP20100185240 |
申请日期 |
1998.02.24 |
申请人 |
EURO-CELTIQUE S.A. |
发明人 |
REDER, ROBERT, F.;GOLDENHEIM, PAUL, D.;KAIKO, ROBERT, F. |
分类号 |
A61F13/00;A61K9/22;A61K9/70;A61K31/00;A61K31/485;A61P25/00;A61P25/04;A61P29/00 |
主分类号 |
A61F13/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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