| 摘要 |
PROBLEM TO BE SOLVED: To provide a mutant type protein having the degree of diaphorase activity or thermostability thereof at a prescribed level or higher. SOLUTION: The mutant type protein is composed of an amino acid sequence in which at least one or more amino acid residues are deleted, substituted, added or inserted in a specific natural type amino acid sequence and has the diaphorase activity with ≥245 value of the enzyme activity. Furthermore, the thermostable mutant type protein has the diaphorase activity with ≥245 value of the enzyme activity and ≥41% residual enzyme activity after a heat treatment. COPYRIGHT: (C)2008,JPO&INPIT |
