Method for producing pyrimidine compound

摘要

A method which comprises reacting the compound of the formula (VI):
(wherein Y is alkyl, arylalkyl or halogen, and p is an integer of from 0 to 3, and each of R 1 and R 2 is methyl, methoxy or ethoxy), with a compound represented by the formula (VII):
(wherein R 3 is -CF 3 or -CON(R 5 )R 6 , R 4 is inter alia halogen, alkyl, haloalkyl, alkoxy, haloalkoxy, alkylthio, haloalkylthio, alkoxyalkyl, haloalkoxyalkyl or -N(R 7 )R 8 , each of R 5 and R 6 is a hydrogen atom, alkyl, haloalkyl, alkenyl, alkynyl, alkoxy, haloalkoxy, alkoxyalkyl, haloalkoxyalkyl, cycloalkyl, halocycloalkyl, alkoxycarbonyl, haloalkoxy-carbonyl, phenyl or halophenyl, provided that when either R 5 or R 6 is a hydrogen atom, the other is other than a hydrogen atom, R 5 and R 6 may form a heterocyclic ring together with the adjacent nitrogen atom, each of R 7 and R 8 is a hydrogen atom or alkyl, n is an integer of from 0 to 2, and m is 0 or 1), to produce a compound represented by the formula (VIII):