| 发明名称 |
Neutralizing human anti-IGFR antibody |
| 摘要 |
The present invention includes fully human, neutralizing, monoclonal antibodies against human Insulin-like Growth Factor Receptor-I (IGFR1). The antibodies are useful for treating or preventing cancer in a subject. Also included are methods of using and producing the antibodies of the invention. |
| 申请公布号 |
US8173779(B2) |
申请公布日期 |
2012.05.08 |
| 申请号 |
US20100941617 |
申请日期 |
2010.11.08 |
| 申请人 |
WANG YAN;GREENBERG ROBERT;PRESTA LEONARD;PACHTER JONATHAN A.;HAILEY JUDITH;BRAMS PETER;WILLIAMS DENISE;SRINIVASAN MOHAN;FEINGERSH DIANE;SCHERING CORPORATION |
发明人 |
WANG YAN;GREENBERG ROBERT;PRESTA LEONARD;PACHTER JONATHAN A.;HAILEY JUDITH;BRAMS PETER;WILLIAMS DENISE;SRINIVASAN MOHAN;FEINGERSH DIANE |
| 分类号 |
C12N15/09;C12P21/08;A61K39/395;A61P1/04;A61P9/10;A61P13/08;A61P17/06;A61P21/00;A61P35/00;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10 |
主分类号 |
C12N15/09 |
| 代理机构 |
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