发明名称 |
Compositions and methods for effecting NAD+ levels using a nicotinamide phosphoribosyl transferase inhibitor |
摘要 |
The present invention relates to methods for decreasing cellular DNA repair in a patient diagnosed with or suspected to have chronic lymphocytic leukemia (CLL); decreasing cellular NAD+ biosynthesis in a patient diagnosed with or suspected to have CLL; or sensitizing a patient diagnosed with or suspected to have CLL to a DNA damaging therapy. The invention relates to methods for treating a patient diagnosed with or suspected to have CLL. |
申请公布号 |
US8173677(B2) |
申请公布日期 |
2012.05.08 |
申请号 |
US20090410930 |
申请日期 |
2009.03.25 |
申请人 |
ROULSTON ANNE;BEAUPARLANT PIERRE;GEMIN X PHARMACEUTICALS CANADA INC. |
发明人 |
ROULSTON ANNE;BEAUPARLANT PIERRE |
分类号 |
A61K31/4545;A61K31/4425;A61P35/02 |
主分类号 |
A61K31/4545 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|