发明名称 |
ISOQUINOLINE COMPOUNDS AND MEDICINAL USE THEREOF |
摘要 |
The present invention relates to an isoquinoline compound represented by the following formula (I) or (II), an optically active form thereof, a pharmaceutically acceptable salt thereof, a water adduct thereof, a hydrate thereof and a solvate thereof, as well as an agent for the prophylaxis and/or treatment of a disease caused by hyperreactivity of poly(ADP-ribose)polymerase, containing the compound, and a poly(ADP-ribose)polymerase inhibitor containing the compound. In addition, this compound is useful as an agent for the prophylaxis and/or treatment of cerebral infarction, particularly as an agent for the prophylaxis and/or treatment of acute cerebral infarction. (see formula I) (see formula II)
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申请公布号 |
CA2507027(C) |
申请公布日期 |
2012.05.08 |
申请号 |
CA20032507027 |
申请日期 |
2003.11.21 |
申请人 |
MITSUBISHI PHARMA CORPORATION |
发明人 |
FUJIO, MASAKAZU;SATOH, HIROYUKI;INOUE, SHINYA;MATSUMOTO, TOSHIFUMI;EGI, YASUHIRO;TAKAHASHI, TAICHI |
分类号 |
C07D217/24;A61K31/472;A61K31/4725;A61K31/4745;A61K31/496;A61K31/5377;A61P9/00;A61P9/10;A61P43/00;C07D401/04;C07D401/06;C07D471/04;C07D498/04;C07D513/04 |
主分类号 |
C07D217/24 |
代理机构 |
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主权项 |
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地址 |
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