发明名称 |
Drying process for preserving an active agent as a highly viscous liquid |
摘要 |
The present invention relates to a method of drying biological and other labile samples so that they can be preserved as a highly viscous liquid. The method involves the steps of preparing a preservation sample by dissolving/suspending an active agent in a solution of a stabilizing agent, subjecting the preservation sample to such temperature and pressure conditions that the preservation sample looses solvent by evaporation without freezing or bubbling to form a foam and removing solvent until the preservation sample dries to form a highly viscous liquid. The stabilizing solution comprises a glass forming polyol and a second component which decreases the flow rate of the highly viscous liquid formed by the method. |
申请公布号 |
US8173411(B2) |
申请公布日期 |
2012.05.08 |
申请号 |
US20050587023 |
申请日期 |
2005.04.28 |
申请人 |
MAYERESSE YVES;GLAXOSMITHKLINE BIOLOGICALS S.A. |
发明人 |
MAYERESSE YVES |
分类号 |
C12N1/00;A61K39/13;A61K39/29;A61K47/26;C12N1/04 |
主分类号 |
C12N1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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