发明名称 |
Isoxazole-isoxazoles and isoxazole-isothiazoles |
摘要 |
The present invention is concerned with isoxazole-isoxazoles and isoxazole-isothiazoles of formula I, having affinity and selectivity for GABA A α5 receptor, their manufacture, pharmaceutical compositions containing them and their use as cognitive enhancers or for the therapeutic and/or prophylactic treatment of cognitive disorders like Alzheimer's disease. |
申请公布号 |
US8173652(B2) |
申请公布日期 |
2012.05.08 |
申请号 |
US20100704548 |
申请日期 |
2010.02.12 |
申请人 |
HERNANDEZ MARIA-CLEMENCIA;JAKOB-ROETNE ROLAND;LUCAS MATTHEW C.;THOMAS ANDREW;HOFFMANN-LA ROCHE INC. |
发明人 |
HERNANDEZ MARIA-CLEMENCIA;JAKOB-ROETNE ROLAND;LUCAS MATTHEW C.;THOMAS ANDREW |
分类号 |
A61K31/5377;A61K31/42;A61K31/454;C07D413/06;C07D413/14 |
主分类号 |
A61K31/5377 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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