NOVEL ENOL PHOSPHATE DERIVATIVES AND THEIR PREPARATION METHOD FROM ALKYNES CATALYZED BY GOLD

摘要

PURPOSE: An enol phosphate derivative and a method for preparing the same are provided to enable synthesis of natural products and physiologically active materials. CONSTITUTION: An enol phosphate derivative is denoted by chemical formula 1. A method for preparing enol phosphate derivative comprises: a step of reacting alkane derivative of chemical formula 2 with a phosphate derivative of chemical formula 4 under the presence of a gold catalyst to prepare kinetic enol phosphate derivative of chemical formula A. The gold catalyst includes AuCl, AuCl_3, AuBr_3, PPh_3AuCl, (C_6F_5)_3PAuCl, (IPr)AuCl, or (IMes)AuCl.