Disclosed herein are compositions and methods for controlling fertility of a female subject. Particularly exemplified are compositions comprising sugar derivatives, such as 2-deoxyglucose, D-mannoheptulose; and/or 5-thio-D-glucose. Also disclosed herein are methods of preserving ova supply in a female subject that involves administering glucose derivatives. The composition typically includes a glucose derivative that affects Foxo3a expression.
申请公布号
WO2012058581(A2)
申请公布日期
2012.05.03
申请号
WO2011US58369
申请日期
2011.10.28
申请人
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.;NICK, HARRY, S.;AIKEN, KIMBERLY, J.;BARILOVITS, SARAH, J.;BICKFORD, JUSTIN, S.;BEACHY, DAWN, E.