LIQUID FORMULATIONS OF LONG ACTING INTERFERON ALPHA CONJUGATE
摘要
Disclosed is a liquid formulation in which a long-acting INFa conjugate that has improved in vivo duration and stability can be stored stably for a long period of time. It comprises a stabilizer comprising a buffer, a sugar alcohol, a non-ionic surfactant and an isotonic agent. Being free of human serum albumin and other potential factors harmful to the body, the liquid formulation is free of concerns about viral infections and guarantees excellent storage stability to long-acting INFa conjugates.
申请公布号
WO2012057525(A2)
申请公布日期
2012.05.03
申请号
WO2011KR08038
申请日期
2011.10.26
申请人
HANMI HOLDINGS CO., LTD.;IM, DAE SEONG;LEE, JAE MIN;LEE, JONG SOO;BAE, SUNG MIN;KWON, SE CHANG
发明人
IM, DAE SEONG;LEE, JAE MIN;LEE, JONG SOO;BAE, SUNG MIN;KWON, SE CHANG