摘要 |
A system capable of visualization of phenomena within a living organism having been exposed to stress by way of molecular biology to thereby carry out quantitative detection thereof; and means capable of stress management. There is provided an indicator agent for noninflammatory stress response wherein superoxides intervene, which indicator agent comprises IL-18. Further, there is provided a visualization agent for noninflammatory stress response used to detect the above indicator agent, and provided a method of assaying the degree of noninflammatory stress, characterized in that use is made of the visualization agent. Still further, there is provided a method of preventing, improving or prognosticating any variation of immune state attributed to noninflammatory stress response, characterized in that the above visualization agent is administered to an animal. Still further, there is provided a therapeutic agent for any variation of immune state attributed to noninflammatory stress response, used to lower the amount or activity of indicator agent mentioned above. |