发明名称 INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY
摘要 This invention relates to compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling and HGF receptor signaling. More particularly, the invention relates to compounds, compositions and methods for the inhibition of VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
申请公布号 US2012108628(A1) 申请公布日期 2012.05.03
申请号 US201113341604 申请日期 2011.12.30
申请人 CLARIDGE STEPHEN WILLIAM;ISAKOVIC LJUBOMIR;MANNION MICHAEL;RAEPPEL STEPHANE;SAAVEDRA OSCAR MARIO;GAUDETTE FREDERIC;ZHAN LIJIE;VAISBURG ARKADII 发明人 CLARIDGE STEPHEN WILLIAM;ISAKOVIC LJUBOMIR;MANNION MICHAEL;RAEPPEL STEPHANE;SAAVEDRA OSCAR MARIO;GAUDETTE FREDERIC;ZHAN LIJIE;VAISBURG ARKADII
分类号 A61K31/4365;A61P43/00 主分类号 A61K31/4365
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