发明名称 |
METHODS AND KITS FOR HIGH EFFICIENCY ENGINEERING OF CONDITIONAL MOUSE ALLELES |
摘要 |
The present invention concerns methods and kits for the direct, targeted engineering of conditional alleles in rodent embryonic stem cells in which the conditional allele is replaced with a DNA of interest without first introducing heterotypic recombination sites, thus providing high efficiency targeted exchange of genetic material. |
申请公布号 |
US2012107938(A1) |
申请公布日期 |
2012.05.03 |
申请号 |
US201013381351 |
申请日期 |
2010.06.28 |
申请人 |
LOPEZ-RIOS JAVIER;ZELLER ROLF;OSTERRWALDER MARCO;UNIVERSITY OF BASEL |
发明人 |
LOPEZ-RIOS JAVIER;ZELLER ROLF;OSTERRWALDER MARCO |
分类号 |
C12N15/87;C12N15/85 |
主分类号 |
C12N15/87 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|