发明名称 |
Cross-Coupled Peptide Nucleic Acids for Detection of Nucleic Acids of Pathogens |
摘要 |
The present invention concerns methods for detecting a nucleic acid comprising (i) contacting a solution comprising a first PNA having a first cross-reactive functional group with a substrate having a second PNA affixed thereto, the second PNA having a second first cross-reactive functional group, wherein the first PNA has a reporter molecule attached thereto and the first and second PNAs being complementary to different portions of a target DNA; (ii) contacting a sample suspected of containing the nucleic acid with the first and second PNAs; and (iii) determining the presence of the reporter molecule on the substrate. |
申请公布号 |
US2012107794(A1) |
申请公布日期 |
2012.05.03 |
申请号 |
US20090409159 |
申请日期 |
2009.03.23 |
申请人 |
APPELLA DANIEL H.;MICKLITSCH CHRISTOPHER |
发明人 |
APPELLA DANIEL H.;MICKLITSCH CHRISTOPHER |
分类号 |
C12Q1/70;C12Q1/68 |
主分类号 |
C12Q1/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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