发明名称 |
ANTIMICROBIAL PEPTIDES |
摘要 |
<p>The present invention relates to antimicrobial peptides, to their use as antimicrobial agents and to their use in the treatment of (infectious) diseases, in particular infectious diseases caused by Gram-positive bacteria, Gram-negative bacteria, yeast or fungi. The present invention further relates to pharmaceutical compositions and kits comprising the antimicrobial peptides and to a method of lysing bacterial, yeast or fungal cells. The antimicrobial peptides consist of one of the following general formula: Wherein X is a hydrophobic amino acid, Y is a cationic amino acid, Z is an amino acid having a free thiol or thioether group, n is 2-4 and m is 0 or 1.</p> |
申请公布号 |
WO2012057713(A1) |
申请公布日期 |
2012.05.03 |
申请号 |
WO2011SG00385 |
申请日期 |
2011.10.31 |
申请人 |
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH;YANG, YI-YAN;WIRADHARMA, NIKKEN;HAUSER, CHARLOTTE, A. E. |
发明人 |
YANG, YI-YAN;WIRADHARMA, NIKKEN;HAUSER, CHARLOTTE, A. E. |
分类号 |
C07K7/08;A61K31/10;A61K38/08;A61K38/10;A61K38/16;A61P31/04;C07K7/02;C07K7/06;C07K14/00 |
主分类号 |
C07K7/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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