The present invention provides novel monoclonal antibodies directed to PIGF and fragments and derivatives thereof, more particularly to humanized antibodies and fragments thereof for use in the treatment and/or prevention of pathological angiogenesis.
申请公布号
EP2447281(A1)
申请公布日期
2012.05.02
申请号
EP20110160897
申请日期
2006.03.24
申请人
THROMBOGENICS N.V.;LIFE SCIENCES RESEARCH PARTNERS;VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW.
发明人
STASSEN, JEAN MARIE;CARMELIET, PETER;COLLEN, DÉSIRÉ