发明名称 |
CONTINUOUS DIRECTED EVOLUTION OF PROTEINS AND NUCLEIC ACIDS |
摘要 |
The present invention discloses generalizable methods of evolving nucleic acids and proteins utilizing continuous directed evolution. The invention discloses methods of passing a nucleic acid from cell to cell in a desired function-dependent manner. The linkage of the desired function and passage of the nucleic acid from cell to cell allows for continuous selection and mutation of the nucleic acid. |
申请公布号 |
EP2342336(A4) |
申请公布日期 |
2012.05.02 |
申请号 |
EP20090812363 |
申请日期 |
2009.09.08 |
申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
LIU, DAVID, R.;ESVELT, KEVIN, M. |
分类号 |
C12N15/10;C12N1/21;C12N15/63 |
主分类号 |
C12N15/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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