Copper-catalysed process for the production of substituted or unsubstituted trifluormethylated aryl and heteroaryl compounds

摘要

The present invention relates to a process for the production of triffluoromethylated unsubstituted or substituted aryl or heteroaryl compounds which comprises reacting an unsubstituted or substituted aryl or heteroaryl halide with a trifluoroacetate of formula (I) or (II),
wherein R 1 is hydrogen or a C 1 -C 5 alkyl group and M an alkali metal or an ammonium ion, in the presence of a copper salt as catalyst and an anorganic halogenide salt or a trifluoroacetacid salt as activator compound.