发明名称 |
Antibodies against interleukin-1 beta |
摘要 |
<p>Antibodies directed to the antigen IL-1² and uses of such antibodies are described. In particular, fully human monoclonal antibodies directed to the antigen IL-1² are discussed. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are described.</p> |
申请公布号 |
EP2361933(A3) |
申请公布日期 |
2012.05.02 |
申请号 |
EP20100183582 |
申请日期 |
2006.01.19 |
申请人 |
AMGEN FREMONT INC. |
发明人 |
GREEN, LARRY;FAGGIONI, RAFFAELLA;FOORD, ORIT;KLAKAMP, SCOTT L.;SENALDI, GIORGIO;SCHNEIDER, AMY K. |
分类号 |
C07K16/00;A61K39/00;A61K39/395 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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