| 发明名称 |
PURIFICATION OF PEGYLATED POLYPEPTIDES |
| 摘要 |
The invention is a method for the purification of mono-PEGylated erythropoietin using two cation exchange chromatography steps wherein the same type of cation exchange material is used in both cation exchange chromatography steps and a method for producing a mono-PEGylated erythropoietin in substantially homogeneous form. |
| 申请公布号 |
EP2178900(B1) |
申请公布日期 |
2012.05.02 |
| 申请号 |
EP20080784775 |
申请日期 |
2008.07.15 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BURG, JOSEF;REICHERT, KLAUS;SCHROTH, AXEL;SCHURIG, HARTMUT;WESSNER, AXEL |
| 分类号 |
C07K1/18;A61K38/18;A61K47/48 |
主分类号 |
C07K1/18 |
| 代理机构 |
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