发明名称 Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment of diabetes
摘要 The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
申请公布号 US8168637(B2) 申请公布日期 2012.05.01
申请号 US20100694758 申请日期 2010.01.27
申请人 EDMONDSON SCOTT D.;KIM DOOSEOP;MACCOSS MALCOLM;PARMEE EMMA R.;WEBER ANN E.;XU JINYOU;MERCK SHARP & DOHME CORP. 发明人 EDMONDSON SCOTT D.;KIM DOOSEOP;MACCOSS MALCOLM;PARMEE EMMA R.;WEBER ANN E.;XU JINYOU
分类号 A61K31/50;A61K31/215;A61K31/35;A61K31/498;A61K31/4985;A61K45/00;A61K45/06;A61P1/02;A61P1/04;A61P3/04;A61P3/06;A61P3/10;A61P5/06;A61P5/28;A61P5/50;A61P7/00;A61P9/08;A61P9/10;A61P9/12;A61P13/08;A61P13/12;A61P15/16;A61P19/10;A61P25/00;A61P25/28;A61P27/02;A61P31/18;A61P35/04;A61P37/02;A61P43/00;C07D487/04 主分类号 A61K31/50
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