| 发明名称 |
1, 5-diphenyl-3-benzylamino-1, 5-dihydropyrrolidin-2-one as CB1 receptor modulators |
| 摘要 |
Compounds and pharmaceutical compositions comprising compounds of the Formula as CB1 receptor inverse agonists useful for reducing body weight in mammals, treating cognitive impairment associated with schizophrenia, and mitigating treatment emergent weight gain observed during treatment with antipsychotics. |
| 申请公布号 |
US8168659(B2) |
申请公布日期 |
2012.05.01 |
| 申请号 |
US20070441570 |
申请日期 |
2007.10.22 |
| 申请人 |
COFFEY DAVID SCOTT;HU JINGDAN;KEDING STACY JO;KRUSHINSKI, JR. JOSEPH HERMAN;SCHAUS JOHN MEHNERT;TUPPER DAVID EDWARD;ELI LILLY AND COMPANY |
发明人 |
COFFEY DAVID SCOTT;HU JINGDAN;KEDING STACY JO;KRUSHINSKI, JR. JOSEPH HERMAN;SCHAUS JOHN MEHNERT;TUPPER DAVID EDWARD |
| 分类号 |
A61K31/4439;C07D401/12 |
主分类号 |
A61K31/4439 |
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