发明名称 |
Use of consensus sequence as vaccine antigen to enhance recognition of virulent viral variants |
摘要 |
The invention provides consensus sequences for hepatitis C virus 1a and 1b. Also provided are non-synonymous changes for each residue of the consensus sequences. These sequences are useful as compositions or vaccines for prophylactic use or treating HCV-infected individuals. Also provided are methods for lessening the chances for a HCV-infected individual to enter a chronic phase of infection and methods of diagnosing an individual with HCV 1a or HCV 1b infection. |
申请公布号 |
US8168771(B2) |
申请公布日期 |
2012.05.01 |
申请号 |
US20060815203 |
申请日期 |
2006.01.31 |
申请人 |
RAY STUART C.;COX ANDREW L.;THOMAS DAVID L.;THE JOHNS HOPKINS UNIVERSITY |
发明人 |
RAY STUART C.;COX ANDREW L.;THOMAS DAVID L. |
分类号 |
C07H21/00;A61K39/29 |
主分类号 |
C07H21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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