| 发明名称 |
Thrombin cleavable factor X analogues |
| 摘要 |
The invention relates to factor X analogues containing the thrombin-cleavable sequence Pro-Arg-Ala in place of the-sequence Thr-Arg-Ile of the activation site of native factor X. These factor X analogues can be used to obtain procoagulant medicinal products. |
| 申请公布号 |
US8168753(B2) |
申请公布日期 |
2012.05.01 |
| 申请号 |
US20050518390 |
申请日期 |
2005.10.25 |
| 申请人 |
LOUVAIN VIRGINIE;BIANCHINI ELSA;MARQUE PIERRE-EMMANUEL;CALMEL-TAREAU CLAIRE;AIACH MARTINE;LE BONNIEC BERNARD;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE |
发明人 |
LOUVAIN VIRGINIE;BIANCHINI ELSA;MARQUE PIERRE-EMMANUEL;CALMEL-TAREAU CLAIRE;AIACH MARTINE;LE BONNIEC BERNARD |
| 分类号 |
A61P7/00;A61K38/00;A61K38/36;A61P7/04;C07K14/745;C12N5/00;C12N9/64;C12N15/00;C12N15/12 |
主分类号 |
A61P7/00 |
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