发明名称 |
Method for modulating insulin production |
摘要 |
The present invention provides screening methods for the detection of agents that affect various aspects of &bgr;-cell biology, particularly insulin gene expression. Screening methods are also provided for detection of agents that affect &bgr;-cell differentiation from progenitor cells. Additionally, agents identified using such methods are provided and are useful for increasing insulin gene expression and reducing lipotoxicity. |
申请公布号 |
US8168391(B2) |
申请公布日期 |
2012.05.01 |
申请号 |
US20080267507 |
申请日期 |
2008.11.07 |
申请人 |
LEVINE FRED;ITKIN-ANSARI PAMELA;MERCOLA MARK;BURNHAM INSTITUTE FOR MEDICAL RESEARCH;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
LEVINE FRED;ITKIN-ANSARI PAMELA;MERCOLA MARK |
分类号 |
C12Q1/68;C12N15/00;G01N33/53;G01N33/567 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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