| 摘要 |
<p>A triazinone derivative represented by formula (I)
wherein:
wherein:
Z represents a bond, a carbonyl group, a methylene group optionally substituted by one or two groups chosen from a C 1-6 alkyl group, a hydroxyl group, a C 1-6 alkoxy group; R1 represents a 4-pyridine ring; R2 represents a hydrogen atom, a C 1-6 alkyl; R3 represents a hydrogen atom, a C 1-6 alkyl group; R2 and R3 may form together a 6 membered cycle with the nitrogens caring R2 and R3 optionally substituted; R4 represents: a phenyl ring, being optionally substituted; n represents 0 to 2; in form of a free base or of an addition salt with an acid.
These compounds are useful as GSK3-² inhibitors.</p> |
